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Safety Evaluation and Provider Decision Framework Before starting any GLP-1 medication, patients with ulcerative colitis should undergo thorough evaluation including disease activity assessment, recent colonoscopy findings, current immunosuppressive therapy, and baseline gastrointestinal symptoms
GLP-1 medications work primarily by reducing appetite and slowing digestion , leading to gradual fat loss over time
A controlled study (PMID: 7777652) found that DSIP did not significantly affect CRH- or meal-induced ACTH and cortisol secretionindicating DSIP does not measurably blunt the human cortisol response, contrary to stress-protective effects suggested by some animal studies
Reading Time: 6 minutes Ozempic made a splashy debut in 2017 with a catchy jingle and celebrity following, and Mounjaro came onto the scene five years later as another impressive type 2 diabetes medication that delivers impactful glucose management results along with significant weight loss
