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Across genotypes, adults with TDT experience worse fatigue and greater physical function, work productivity, and daily activity impairments than the general US population
However, GLP-1 medications go a step further by not only improving insulin response but also by suppressing appetite and delaying gastric emptying , leading to more significant weight loss
Your GP or diabetes specialist nurse can review your treatment plan, adjust doses if necessary, or explore alternative medications if Rybelsus is not suitable for you
In the STEP 1 trial (NEJM, 2021), semaglutide 2.4mg achieved a mean weight reduction of 14.9% over 68 weeks versus 2.4% placebo establishing a benchmark that subsequent compounds including retatrutide have sought to surpass
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