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Whilst human studies demonstrating an impact on cognitive decline are still lacking, the current evidence points towards these drugs having a preventative effect, rather than in patients with established cognitive impairment

Additional risks include gallbladder disease and acute kidney injury in the setting of severe gastrointestinal adverse events

Metabolic Boost : Unlike dieting, which can slow metabolism, these medications help maintain energy expenditure, ensuring the body continues to burn calories

Conclusions Compared with TZD, GLP-1RA had better effects on liver fat content, body mass index, and waist circumference in overweight or obese patients with NAFLD or NASH