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Histological studies showed amyloid plaques in the cortex and hippocampus beginning at 11 months, without evidence of NFTs

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Thus, the enzymatic reduction of roGFP2(S 2 ) by GSH follows monothiol mechanism (iii) and requires a glutaredoxin to form roGFP2(SSG)

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doi:10.3109/09513590.2015.1080680

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