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It is a molecule naturally produced by the human body, and decades of clinical use across both topical and injectable applications have not identified significant adverse effects
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doi: 10.4103/0973-7847
375,515 Through TGR5 activation, secondary BAs also modulate the hepatic inflammatory response by inhibiting LPS-induced cytokine expression in macrophages, thereby reducing hepatocyte necrosis and contributing to liver repair after PHx
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