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The general principle these definitions reflect is a pharmacokinetic property rather than a dosing instruction: with a half-life of roughly one week, exposure declines gradually rather than abruptly across a shifted or missed interval
LM-MS/MS, liquid chromatographymass spectrometry
Its short halflife and rapid turnover make it a dynamic biomarker for cellular redox status
[234] Adjusting calcium levels within the Bruch membrane might offer potential treatments to mitigate Bruch membrane disruption and decrease the occurrence of choroidal neovascularization (CNV) in conditions such as myopia, PXE, or AMD
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