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2007 reported that GHK-Cu stimulated dermal papilla cell proliferation by up to 70% in vitro and was associated with an extended anagen phase in their model
IV and short-duration oral trials METAOD001-004 enrolled smaller groups of healthy or obese men with single doses or 1-week dosing across IV (25-400 mcg/kg) and oral (9-54 mg) routes
This significant discrepancy between physiological requirements and therapeutic doses highlights the need for a deeper understanding of B12 absorption dynamics, rather than focusing solely on intake quantity
It also produces information on heavy metal toxicity or anti-oxidant levels, which can be very helpful in understanding symptoms such as tiredness, insomnia or stress and highlighting detoxification requirements
