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It should be noted that the evidence for these extracts remains largely preclinical (in vitro and in vivo animal models)
68 The importance of ZO-1 in TJ stability is illustrated by research showing that barrier stringency is compromised when ZO-1 expression is reduced or dissociated from membrane proteins
While promising in clinical studies, it remains investigational in many jurisdictions
Comparative efficacy In human clinical studies, epitalon and epithalamin both significantly increased telomere lengths in elderly patients aged 60 to 65 and 75 to 80
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