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Potential drug interactions with berberine include: Blood thinners like clopidogrel (Plavix) Cyclosporine (Neoral, Sandimmune) and tacrolimus (Prograf), drugs used to prevent organ rejection Dextromethorphan (Robitussin DM), a cough suppressant Diabetes drugs such as metformin (Glucophage) Losartan (Cozaar), a blood pressure drug Sedatives like zolpidem (Ambien) and pentobarbital (Nembutal) Because berberine acts on the liver, it could cause interactions with other medications processed by this organ
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Involvement of different human glutathione transferase isoforms in the glutathione conjugation of reactive metabolites of troglitazone
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