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Escalation should depend on response, side effects, hydration, nutrition, and the patients ability to function normally

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Not all GLP-1s are approved for obesity treatment, and this analysis includes all FDA-approved GLP-1s, including those approved for obesity (Saxenda, Weogvy, Zepbound) as well as those approved for type 2 diabetes (see Table 1)

The temporary program, running from July 2026 through December 2027, does not change the current statutory prohibition on Medicare coverage of drugs used for weight loss but instead is being established using the federal governments Section 402 demonstration authority