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For osteoarthritis , NICE guidance (NG226) recommends a holistic approach: Education and self-management : Understanding the condition and strategies to manage symptoms Exercise and physical activity : Strengthening exercises, aerobic activity, and local muscle strengthening programmes Weight management : For those who are overweight or obese, structured weight loss programmes Pharmacological options : Topical NSAIDs as first-line

Vomiting is typically most common during the first 48 weeks of treatment and following dose increases

Skin whitening treatments are sought after not only for cosmetic reasons but also to address issues such as hyperpigmentation, dark spots, and uneven skin tone