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Lack of regulatory guidance: Clinicians must obtain informed consent and monitor closely for safety, tolerability, and efficacy
Subsequently, Nuclear Factor Erythroid 2-related Factor 2 (NRF2) was identified as a transcription factor involved in regulating gene expression at these ARE sequences (Ma et al., 2004)
Their ability to improve metabolic health while exerting anti-inflammatory and immunomodulatory effects makes them uniquely interesting for autoimmune conditions
Based on potential binding regions predicted by JASPAR database, we designed specific primers targeting the binding site between c-Myc and the miR-29b-3p promoter (Table S2)
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