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Other research has been limited, mixed, or difficult to apply to modern clinical practice
Note: Updated 6/13 to incorporate AEI and TPC dynamic estimates.
Gastrointestinal distress affects roughly 28% of users at higher doses, with nausea being the most commonly reported complaint
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Most observed benefits are more plausibly explained by paracrine signaling, antioxidant activity, immune-metabolic regulation, angiogenesis, BBB stabilization, mitochondrial support, and enhancement of endogenous plasticity [20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35]
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