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5.3 Exercise-mediated regulation of NO bioavailability, angiogenesis, and mitochondrial dynamics At the convergence of these physiological adaptations, physical exercise facilitates significant modifications in NO bioavailability, angiogenesis, and mitochondrial dynamics

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Each of the participants took 100 micromoles of sulforaphane (from a standardized broccoli sprout extract) by mouth every morning for one week

That means no coffee for potentially 35-40 minutes after waking