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After excluding individuals with pre-existing neurodegenerative or cerebrovascular disease, the study compared 30,430 patients using GLP-1RA therapy (semaglutide or tirzepatide) with 30,430 patients prescribed other antidiabetic agentsincluding biguanides, sulfonylureas, dipeptidyl peptidase 4 inhibitors, and sodium-glucose cotransporter 2 inhibitorsusing propensity score matching to control for baseline differences

But they work in different ways

In children 12 years and older, the rate was 4% versus 0% with placebo

Evaluating these sources requires more ongoing vigilance and periodic verification of product quality