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If you are feeling fatigued this spring, B12 deficiency is one possible explanation worth investigating but so are thyroid dysfunction, iron deficiency, sleep disorders, and numerous other conditions
Mol Cell Neurosci 105:103493
Matera MG, Calzetta L, Cazzola M
Because both rapid degradation and de novo production of cytokines and other proteins occur inside of sample tubes (187, 191), without fast and careful processing, cytokine measurements may reflect processes that happened inside of a sample tube and not what happened in the bodies of study participants
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