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most people eventually stop taking a GLP-1, with estimates reaching as high as 92%
The effects of acetyl-L carnitine (compared or not to gabapentin) on compression neuropathy were studied in a rat model of sciatic nerve compression obtained through loose nerve ligation or transection [16, 43, 44]
The main barriers are bioavailability (how much drug actually enters the bloodstream), stability (peptides degrade when exposed to skin temperature and enzymes), and patient compliance (patches still require weekly changes and site monitoring)
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