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Interpretation requires receptor-selective controls, the exact molecular form, and model-specific primary literature
However, contrary to expectations, the deletion of the Nfe2l2 gene had a moderate impact on the course of the disease in SOD1 G93A mice and negatively affected only a few Nrf2-regulated antioxidant enzymes, thus suggesting that several Nrf2-target genes can also be regulated independently of Nrf2 in ALS mice [270, 271]
Follow-Up Guidance: Patients are advised on timing, storage, and handling of the medication
Overuse: Repetitive motions like typing or running, often affecting athletes and those with repetitive job tasks
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