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When assessing TH1- and TH2-related cytokines separately, we observed that females had higher levels of TH2-related cytokines than males (main effect of sex for TH2: F (1,55) = 4.615, R 2 = 0.083, p = 0.018), but not TH1-related cytokines, nor were there any other significant main effects or interactions present, although there was a trend towards a diet effect (main effect of diet: p = 0.060
Pharmacokinetic modeling in swine confirmed dose-dependent GH release with an ED50 of 2.3 nmol/kg and Emax of 65 ng GH/mL plasma (Johansen et al., 1999)
In fact, the only study that I could find involving humans was a very small retrospective study with just 16 participants
Statistical analysis Using data generated from a pilot study and G*Power 3.1 software (Dsseldorf, Germany), it was determined that a sample size of 15 would provide 80% power to detect an increase in CNS GSH concentrations between pre- and post-administration values, with an accepted alpha value of 0.2
