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View Study [4]"Development of Cagrilintide, a Long-Acting Amylin Analogue" Kruse T et al., 2021 Finding: Describes the medicinal chemistry development of cagrilintide, explaining how lipidation extended the half-life from minutes (pramlintide) to approximately one week while maintaining receptor activity

The study found that Body weight and body composition were maintained one year after termination of supervised exercise, in contrast to weight regain after termination of treatment with obesity pharmacotherapy alone. Dr Winnett recommends encouraging your patients to just get moving: at least 30 minutes of exercise per day, five times per week, including ideally two or three sessions of weight-bearing exercise a week. 6

HbA1c reductions were 1.7% at 4 mg, 2.0% at 9 mg, and 1.9% at 12 mg, compared with 0.8% on placebo

Who is a good candidate for GLP-1 maintenance