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Slow Heart Rate A slow heart rate can indicate an overdose, especially if it is accompanied by respiratory depression

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However, potential side effects can include: Nausea or dizziness (rare) Headaches Injection site irritation Overstimulation or fatigue if overdosed There are no long-term human trials, so effects on hormones, organs, or chronic use remain unknown

The effect of antioxidants (N-acetylcysteine and melatonin) on hypoxia due to [PMID: 20586144] Laboratory literature summary: The effect of antioxidants (N-acetylcysteine and melatonin) on hypoxia due to carbonmonoxide poisoning