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Once we reach this steady state, its recommended to aim for a weight-loss rate of around 0.5-1 lb per week to reduce the risk of muscle and bone loss, hair loss, and nutrient deficiencies
Surgery 149 (5), 713724 (2011)
A Phase 2 randomised controlled trial published in the New England Journal of Medicine in 2023 (Jastreboff et al., NEJM 2023) reported that participants receiving higher doses of retatrutide (up to 12 mg) achieved mean body weight reductions of approximately 1724% over 48 weeks
Most people stop Ozempic after two years
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