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Strode C, Wondji CS, David J-P, Hawkes NJ, Lumjuan N, Nelson DR
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Given the impact of MTHFR polymorphisms on methylfolate production, nuclear methylation, and the production of monoamines, there has been considerable research examining the association between MTHFR genetic variations and psychiatric disease states including unipolar depression, bipolar depression, schizophrenia, and more
However, equilibrium dialysis data 8 and direct EPR measurements 9 showed that HSA competes effectively with His for binding of Cu(II) at equimolar concentrations suggesting that excessive concentration of HSA in the blood serum should avoid the binding of Cu(II) to His and other free amino acids in the blood
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