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You start on a low dose for safety, to minimise potential side effects
(1998) The foundational selectivity study
However, in our study, oxidative stress-induced cell death was triggered by lipid peroxidation instead of the canonical mitochondrial ROS accumulation
Briefly, glutathione was sequentially oxidized by 5-5' dithio-bis (2-dinitrobenzoic acid) (DTNB) and reduced by NADPH in the presence of glutathione disulfide reductase, which results in the formation of 5-thio-2-nitrobenzoic acid (TNB)
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