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PLoS One 6:e27260
That said, DEXA is certainly imperfect in splicing the details of this body composition change as adipose tissue includes plenty of lean mass. Additionally, the placebo group lost more lean mass (-1.83kg) than fat mass (1.37kg), which shows potential error. Nadolsky pointed out that rapid weight loss, in general, will reduce resting metabolic rate to some degree
The patients were randomized to different groups
By week 48, participants on 12mg had lost an average of 24.2% of their body weight
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