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A screen for the candidate insertion site and further validation in C2C12 single-cell colonies To search for an appropriate integration site for the MLC enhancer, we divided the region 100 kb upstream the Igf1 transcriptional start site into non-overlapping 50 bp windows, and calculated average PhastCons score from the UCSC database for each window 35
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However, despite encouraging findings, clinical translation remains limited due to the lack of sufficient human studies, variability in individual responses, and an incomplete understanding of their mechanisms in sepsis
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