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An alternative approach aiming to maximize the efficacy of GLP-1 involves the delivery of nuclear receptor agonists to specific tissues characterized by the expression of GLP-1R
Recent studies 58 have yielded conflicting results regarding the potential relationship between GLP-1 RAs and optic nerve pathologies, particularly non-arteritic anterior ischemic optic neuropathy (NAION)
All patients that satisfied these criteria were included, resulting in a final sample of 40 hypothyroidism (age mean 46 years, range 20 79 years, 4 males) and 12 CFS (mean age 43 years, range 23 68 years, 3 males) patients
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