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Nor Hanipah Z, Nasr EC, Bucak E, et al

The IGF pathway regulates ER through a S6K1-dependent mechanism in breast cancer cells

In this respect, 300 nM Ex-4 during differentiation reduced lipid accumulation and downregulated the adipogenic markers PPAR , FABP4 , whereas early exposure at cell isolation or prior to induction increased these markers, indicating pro-adipogenic priming effects