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(2021) demonstrated that MOTS-c levels decline with age in both mice and humans, and that exogenous MOTS-c administration improved physical capacity in aged mice without observable toxicity over a 2-week treatment window [5]

If you take large doses of vitamin B12 and notice adverse side effects, talk to your health care professional about the issue and ask about evaluating your ability to properly absorb the nutrient

That makes the two a clean structural pair for isolating the modifications effect

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