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8,9 Generally, released GLP-1 from intestinal L cells bind onto canonical receptors in the pancreatic islet, after oral glucose load, or may indirectly signal the hepatic vagal branch within intraportal vein, thereby promoting glucose-dependent insulin secretion from the pancreatic -cells, concurrently causing inhibition of glucagon secretion, and enhancing insulin gene transcription
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DOI: 10.1210/jc.2011-1851
Adults typically need 2.4 mcg of B12 and 600-800 IU of vitamin D daily to maintain health
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