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If you have mild insulin resistance without significant obesity and want to reduce medication burden, metformin remains a solid foundational option
The current evidence base for GLP-1 receptor agonist therapy is derived from extensive clinical trial programmes that have established the efficacy and safety of specific, licensed doses
The first study, PIONEER 5, is reviewed above
Over a year, this could result in thousands of dollars in savings without sacrificing the potential for weight-loss success
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![PDF] l‐Carnitine and heart disease](https://figures.semanticscholar.org/b5793411365f90c7a7e2d59ac224313ee4306590/4-Figure2-1.png)
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