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With wide roads, large parking lots, and sprawling commercial centers, there can be a lack of encouragement for pedestrian activities

They may include: cold sweat, cool pale skin, headache, fast heartbeat, feeling sick (nausea) or feeling very hungry, changes in vision, feeling sleepy or weak, feeling nervous, anxious or confused, difficulty concentrating, or shaking

Healthcare providers can adjust the treatment regimen by slowing dose escalation, temporarily reducing the dose, or prescribing antiemetic medications when appropriate

Moreover, there are differences in laboratory assessment methods in different trials, as well as differences in intra assay coefficient of variation (intra-assay CV) and inter-assay coefficient of variation (inter-assay CV)