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That's a reason to keep on top of your nutrition and strength-training while on these drugs, he writes, "especially for older people like me, who are [already] susceptible to muscle loss." There are people who should steer clear of GLP-1 drugs, Kessler notes, including those with a personal or familial history of certain thyroid and endocrine cancers, those with chronic kidney disease, pancreatitis, inflammatory bowel diseases, uncontrolled diarrhea or constipation or gastroparesis, or if you are pregnant

To mitigate the well-established risk of DKA, patients were required to have a total daily insulin requirement of 0.5 U/kg, undergo frequent home ketone monitoring and receive structured education [28]

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Skin looks smoother, firmer and more supple by morning