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This is in agreement with our previous study in which tamoxifen-resistant cells were reported to have high GLUL levels [22], which was attributed to the activation of the PI3K/AKT/PTEN signaling pathway, which is known to increase proliferation and cellular invasion [33]
Pharmacological studies suggest that alleviating migraine nociceptive sensitization may be achieved through enhancing endogenous antioxidant defense systems and targeting anti-inflammatory pathways (45, 46)
It had also been discounted for the treatment of obesity because there was some prec-clinical evidence to suggest it was linked with weight gain
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