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Clinical trials are needed to validate antagonist efficacy and safety
Upon binding, it initiates a signal transduction pathway involving the cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA) systems
Recent investigations (20232025) have moved beyond simple association to elucidating precise molecular mechanisms, particularly involving the gut-pancreas axis, incretin hormone regulation, and the mitigation of systemic oxidative stress (434)
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