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These in vitro findings cannot be transferred to the treatment of humans and require further research
Abruptly stopping a GLP-1 medication isn't dangerous, but it can lead to a rapid return of appetite and, over time, weight regain
The phase 2 dose-ranging trial (NCT02970942) included 320 individuals with histologically proven MASH and hepatic fibrosis F1-F3, randomizing them 3:3:3:1:1:1 to daily subcutaneous administration of semaglutide 0.1, 0.2, or 0.4 mg, or placebo for 72 weeks [18]
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