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Use comfort-first textures and add soothing/barrier supports Provide a start slow plan for sensitive users Avoid asking consumers to stack too many strong actives at once 5
Co-ligand bonding and the trans effect
Documented monitoring consideration: because new or darkening pigmented lesions are a documented effect (Minder et al., 2013), dermatology literature describes baseline and periodic skin checks for those on melanocortin agonists
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