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Warnings and precautions Severe adverse effects are rare, but may include: Acute (sudden) pancreatitis or inflammation of the pancreas, the organ that makes insulin and digestive juices Increased heart rate Gallbladder issues, such as inflammation or gallstones Gastroparesis, a condition that affects the muscles and nerves in the stomach and slows down food digestion Some populations may experience complications or risks with these medications
Literature Search Strategy A structured search of PubMed/MEDLINE, Embase, and Web of Science was conducted on 18 April 2026 for studies published between January 2005 and April 2026
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