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Cao H, Xu Y, de Necochea-Campion R, Baylink DJ, Payne KJ, Tang X, et al
Future clinical directions will likely focus on standardized protocols, improved formulation quality, and clearer delineation between evidence-supported and investigational uses
Therapeutic Applications: Cellular Senescence: Age-related decline in cellular function and vitality DNA Damage Accumulation: Environmental and chronological genomic stress Mitochondrial Dysfunction: Impaired cellular energy production systems Metabolic Dysregulation: Altered cellular metabolism and repair processes Inflammatory Aging: Chronic low-grade inflammatory responses Oxidative Stress: Free radical damage and antioxidant system decline Cellular Optimization Mechanisms: NAD+ serves as a crucial cofactor in cellular energy metabolism, DNA repair processes, and gene expression regulation
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