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Some studies have demonstrated the ability of gut-derived GLP-1 to cross through the blood-brain barrier and thoroughly perfuse the brain parenchyma, but whether its effects are similar to that of PPG-derived GLP-1 remains to be established [50, 53]
Diabetes Care 38(12):22582265
Additionally, it occupies GIP receptors and mimics the action of the GIP hormone to enhance insulin release and promote fat breakdown
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