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Earlier clinical trials painted a stark picture: stop the drug, regain the weight
Pharmacol Toxicol 1988
Semaglutide Functions primarily as a GLP-1 receptor agonist Helps regulate appetite and satiety Widely used in medical weight-loss programs Tirzepatide Targets both GLP-1 and GIP pathways Provides dual hormone activity May produce greater average weight loss in some patients The best option depends on several factors, including medical history, treatment goals, medication tolerance, and provider recommendations
The effect is consistent throughout the investigations, as evidenced by no heterogeneity (I 2 = 0.0%)
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