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Most patients in the trial were able to have a 5% weight loss while people who received 10 mg or 15 mg doses demonstrated 20% reduction in body weight
Changes in SPARC level in our study were correlated with changes in circulating levels of decorin, which is a collagen-associated extracellular matrix proteoglycan that promotes the formation of bone matrix and calcium deposition to regulate bone morphogenesis [26]
These establish a before-picture
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