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It inhibits inflammation-induced carcinogenesis in the gut It is a tumor suppressor Mitochondrial glutathione forms the mitochondrial sheath of spermatozoa which contributes to male fertility

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The low GSH concentration necessary for CVA21 displacement may also limit a co-elution of potentially bound host cell GST enzymes present in cell culture harvests, which may require as high as 10 mM GSH for elution (Figure 4A) and elution NaCl gradient (Supplementary Figure S6C) studies where CVA21 particles eluted at lower ionic strengths with increasing pH

Biology Bulletin of the Russian Academy of Sciences, 46 , 407-414