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For optimal absorption and efficacy, especially regarding the chelating properties of modified citrus pectin and the amino acid absorption of NAC and l-methionine, it is generally recommended to take this supplement between meals, on an empty stomach

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One retrospective study of intra-articular knee injections reported symptomatic improvement lasting over six months following a single injection in 7 of 12 patients, suggesting potential for sustained effects beyond active treatment periods

The events were most common among people 65 and older and people with diabetes