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Reconstituted working solutions are typically held at 28 C and used within weeks, with aliquoting to minimize freeze-thaw degradation
Randomized 1:1:1:1 to tirzepatide 5 mg, 10 mg, 15 mg, or placebo for 72 weeks
Although exercise for weight loss can increase energy expenditure, for some obese people, due to the heavy physical burden and limited exercise capacity, it is difficult for them to persist in high-intensity exercise
28.2% for controls (Pickart & Margolina, 2018)
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