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It was demonstrated, that metabolic disturbances in hypothalamic astrocytes, caused either by selective knock-out of insulin receptors or decreased generation of reactive oxygen species (ROS) modulated glucose transport via BBB and also led to modification in behavioral responses in experimental animals [95, 96]
Phospholipids are degraded at the sn -2 (C2) position by pancreatic phospholipase A 2 releasing a free fatty acid and the lysophospholipid
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