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Macrophages are the most abundant immune cell in adipose tissue, with higher numbers of macrophages coinciding with greater severity of obesity [122]
Its mechanism of action remains an active area of investigation, with researchers exploring interactions between this peptide and multiple signaling networks involved in cellular repair and cytoprotection
Frontiers in Cellular Neuroscience
The protein level of significantly increased p16 was confirmed in keloid lesions and fibroblasts based on western blot analysis ( p = 0.0007, p = 0.03
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