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Slightly more nerdy answer: because peptides are small, they can bind directly to cell receptors and trigger specific biological effects

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JAMA 2022;327:534-45.ArticlePubMedPMC 129

Aseptic Operation and Packaging Aseptic operation Clean workshop: The preparation of cream must be carried out in a clean workshop that meets GMP standards, and the air cleanliness should reach Class 100 or Class 1000 standards