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GLP-1 receptor agonists are synthetic analogs or modified versions of this endogenous hormone, designed to resist degradation by the enzyme dipeptidyl peptidase-4 (DPP-4), thereby extending their duration of action from minutes to hours or days
Despite their therapeutic efficacy, they are associated with metabolic side effects, most significantly steroid-induced hyperglycaemia (SIH) and steroid-induced diabetes (SID)
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The pcDNA3.1(+)-GSTA2X was used as a template to amplify the cDNA fragment encoding GSTA2X protein
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