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Similarly, it leads to the downregulation of Akt, HIF-1, NF-B, and VEGF in OVCAR-3 ovarian cancer cells and suppression of TRIF/receptor interacting serine/threonine kinase 1 (RIPK1)/Fas associated via death domain (FADD), TRIF protein, caspase-8, and TLR3/IRF-3 in LNCaP and PC-3 cell lines (300, 301)

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Supplementation with 1.35 g/day of EPA + 0.3 g/day of DHA did not affect innate immune functions in either young or older men

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Rheumatology (Oxford) 64, 3085-3089 (2025)

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The study selection process and report counts are summarized in Supplementary Fig

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